CRISPRs have transformed the world of genome editing, opening up great potential and exciting opportunities for understanding the relationships between genes and phenotypes.  At the GRCF, we have partnered with four innovative companies to provide you a broad range of products to assist you in every aspect of this rapidly moving field.  Agilent provides custom sgRNAs for CRISPR with full in-house support.  Dharmacon and IDT both provide online tools for design assistance.  Sigma, through our CRISPR Core Partnership provides detailed, in-person assistance. For more information on various products and types of assistance offered by each company, see their specific pages in the left menu.


Pricing is dependent on product and company selected.  Many items require a custom quote.  See the information for the individual companies in the menu on the left.



Fill out the spreadsheet linked below and email it to us.  We will connect you with Agilent and provide a quote for the requested items.


Dharmacon and IDT provide online ordering through their portals.

Dharmacon IDT


If you design your own CRISPRs and wish to order them through MilliporeSigma, you can now do so using our form on iLab.  Once you place your order, our staff with pass it along to MilliporeSigma and it will be delivered with your CoreStore orders.

MilliporeSigma iLab form

To order some the highly customized products offered by MilliporeSigma, orders are placed through individual quotations.  Pre-designed assays are also ordered using this mechanism. Using the ordering instructions, complete the pre-designed or custom order form and email it to  Our local sales specialists are always available to assist.  Feel free to contact Michelle Laird and Zulfiquer Hossain with any questions.  Because we are a member of the MilliporeSigma CRISPR Core Partnership program, special pricing and assistance is available to our customers. Working together, we will provide you with cost effective, high quality products, full technical support, early access to new technology, scientific seminars and webinars, a diverse portfolio, and global networking events. Through this program, Sigma-Aldrich will do all of the design and construction work for you supplying ready-to-transfect/transduce CRISPRs in the following formats:

  • All-in-one vector
  • Dual vectors (Cas9 and gRNA separate)
  • Paired nickases
  • mRNA
  • Lenti virus

*Ordering lentivirus vectors from any of these sites requires that investigators have a current recombinant
DNA and infectious agent registration for this material from the Johns Hopkins Biosafety Office.