We Offer the Full Line of Illumina Genotyping Arrays

Global Screening Array

The Infinium Global Screening Array (GSA) combines multi-ethnic genome-wide content, curated clinical research variants, and quality control (QC) markers for precision medicine research. The 640,000 genome-wide markers were selected for high imputation accuracy at minor allele frequencies of >1% across all 26 1000 Genomes Project populations. The array provides a genomic tool for clinical research applications including disease risk profiling studies, pharmacogenomics research, wellness characterization, and complex disease discovery.

Global Diversity Array

The Infinium Global Diversity Array (GDA) is the commercial version of the array chosen by the All of Us Research program. This array was designed to meet the needs of the program’s goals of genotyping the rich diversity of the United States. As such, the markers chosen for the array combine highly optimized multi-ethnic, genome-wide content with curated clinical research variants. The array is highly informative, with a backbone optimized for cross-population imputation coverage of the genome. It also enables polygenic risk score development and characterization of genetic architecture in diverse populations.

GSA

94 – 4,999 samples

$110

per sample

Price for 95-5,000 samples.
Have between 47 and 95 samples? Add $10/sample. Minimum project size is 47 samples.
Have 5,000 or more samples? Please inquire about discounts.
Need pretesting? Add $35/sample

GDA

94 – 4,999 samples

$135

per sample

Price for 95-5,000 samples.
Have between 47 and 95 samples? Add $10/sample. Minimum project size is 47 samples.
5,000 or more samples: $125/sample
Need pretesting? Add $35/sample
Add-on content such as the PGx booster, Neuro booster, PRS booster, etc, is available for additional fee

What’s included?

Our full service pricing includes:

  • All reagents
  • One HapMap controls per 96 well plate
  • 1 blind duplicate every other plate.
  • Repetition of any sample which has less than a 96.5% call rate for an Illumina array. We attempt the GWAS assay only twice.
  • Full data release, which includes: hapmap concordance, reproducibility of genotype calculations broken down by MAF bin for each sample pair,
  • GenomeStudio project, SNP and samples tables, full SNP technical filter applied, samples reclustered on own data, final reports, PLINK file and README docs explaining the data in each directory

What does pretesting include?

  • Pretesting on the Illumina QC array (15,000 snps used to barcode the sample)
  • Prediction of sample performance
  • Verification of gender & family relationships
  • Problems report provided prior to run on GWAS array
  • Opportunity to replace problem samples prior to running the sample on the GWAS array.

What if I want a different level of service?

Other pricing options exist, including ones with no controls or redos, no pretesting, raw data only and combinations of each of these. Please inquire for pricing for these other options. Assistance with plate map design, data cleaning, imputation and upload into dbGAP and other databases are available. Please inquire for pricing.

Are other arrays available?

We offer any array Illumina manufactures. This page lists the most popular, current arrays. If you are interested in an array which is not listed, please contact us.

Sample Requirements

  • 50 ul of genomic DNA at a concentration of 30-50 ng/ul in 1xTE (10mM Tris, 1mM EDTA, pH8) or water.
    * Uniform Volumes are required.
    * Genomic DNA, even at low concentrations is generally preferred over Whole Genome Amplified (WGA) samples. Please discuss your sample quality and quantity with your project manager before deciding which samples to send.
    * Highly fragmented (FFPE or degraded) samples may be used with the restore process, which adds $100/sample to the cost.