Oligonucleotides – Custom RNA and DNA Synthesis
GE Dharmacon RNA synthesis chemistry provides researchers with high-quality custom single-stranded RNA, siRNA, synthetic sgRNA, and microRNA with an extensive range of modifications, synthesis scales, and purification choices. Also available are DNA only oligos, as well as RNA:DNA hybrids.
- Benefits of 2′-ACE synthesis chemistry
- Extensive chemical modification options for RNA synthesis
- Long, high yield single-stranded RNA
- High performance siRNA with proprietary modifications
- “Have it your way” with post synthesis options
Design tools are also available! Please login to the ordering site prior to starting a design, so that your custom order will be properly linked to the portal.
siDESIGN Center
- The siDESIGN Center is a free online design tool that offers the power of the Dharmacon SMARTselection algorithm for the custom design of highly functional siRNAs.
CRISPR RNA Configurator
- The tools in the CRISPR RNA Configurator allow you to quickly and easily generate guide RNA sequences for ordering, either as synthetic crRNA or lentiviral sgRNA.
Edit-R HDR Donor Designer
- Quickly and easily design and order a donor template for precise CRISPR-Cas9 gene editing. Custom-synthesized ssDNA donor oligonucleotide (oligo) templates for precise insertion, removal, or replacement of genomic DNA can be rapidly designed and ordered with this powerful online tool.