siRNA                          shRNA

siRNA

Advanced siRNA design and quality synthesis are crucial for a successful RNA interference experiment. MilliporeSigma’s predesigned siRNA and siRNA libraries were designed using the Rosetta siRNA Design Algorithm to reduce off-target effects and provide guaranteed gene silencing. Coupled with our custom siRNA synthesis services and siRNA transfection reagents, we offer industry-leading technologies that enhance RNAi research.

For in vivo research, MilliporeSigma® provides MISSION® In Vivo Quality and iScale Oligos™ siRNA that deliver highly purified siRNA at the quantity necessary for successful in vivo experiments. Our expertise in oligo manufacturing allows us to offer a variety of modifications and scales suitable for any stage in your in vivo research.

Pricing:
  • 2 OD (10 nmol): $72.00
  • 5 OD (25 nmol): $140.00
  • 10 ID (50 nmol): $168.00

See price list for details.

Order now

Please note that prior to ordering, you must set up a GRCF portal specific account with MilliporeSigma by emailing us with the following information:

  • Your name
  • Your email address
  • Your phone number
  • Your Building and room number (for delivery)
  • Your PI’s name

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shRNA

When you partner with MilliporeSigma’s MISSION RNAi team, you gain access to the extensively validated genome-wide TRC shRNA libraries, flexible lentiviral shRNA custom services, and ideal screening formats designed to accelerate your RNAi discovery. Save time and resources when you take advantage of the MISSION team’s world-class expertise in high-throughput lentiviral manufacturing and DNA purification services. We offer unparalleled gene coverage with our new TRC1.5 library and TRC2 clones available exclusively through Sigma® Life Science.

As a collaborative member and distributor of TRC1.5 and TRC2, MilliporeSigma offers multiple formats of the TRC1.5 lentivirus-based shRNA library consisting of almost 200,000 pre-cloned shRNA vectors targeting more than 22,000 human and 20,000 mouse genes. Whole-genome TRC shRNA libraries, individual RNAi clones/vectors, or shRNA gene family sets (gene panels) are available in the standard glycerol format as well as the higher quality DNA and lentiviral formats exclusively from Sigma.

Pricing:

shRNA FormatIndividual PriceClone Set* (price/clone)
Glycerol stock$65.00$39.00
Plasmid DNA$255.00$102.00
Lentiviral particles$245.00$98.00
* A clone set is 5 clones except when a lesser quantity is available.

See price list for details.

Order now

Please note that prior to ordering, you must set up a GRCF portal specific account with MilliporeSigma by emailing us with the following information:

  • Your name
  • Your email address
  • Your phone number
  • Your Building and room number (for delivery)
  • Your PI’s name & email address

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